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1. Dissolving salt in water is an example of which type of change ?
Physical-Answer
Nuclear
Chemical
Biochemical
2. When nuclear change takes place, which is true
Energy is destroyed
Energy is released-Answer
Energy is changed
None of these
3. Which type of radiation is unaffected by magnetism ?
Alpha
Beta
Gamma-Answer
All of these
4. Which temperature scale is an absolute scale, where the zero point is the lowest possible temperature ?
Kelvin-Answer
Celsius
Fahrenheit
Centigrade
5. The relative randomness of molecules in the states of matter is best indicated by
Solid > Liquids > Gas-Answer
Liquid > Gas > Solid
Liquid > Solid > Gas
Gas > Liquid > Solid
6. Whether or not two liquids are miscible is determined by
Molecular Size : Molecules of similar sizes tend to mix together
Density : Liquids of simliar densities usually mix well together
Polarity : Polar and nonpolar liquids are not miscible while polar liquids can usually be mixed with each other-Answer
All of the above factors directly affect miscibility
7. The Triple Point is
The combination of standard temperature, pressure and volume
The combination of temperature and pressure at which the solid, liquid and gas phases can coexist at equilibrium
The combination of pressure and temperature at which liquid, gas, and plasma phases all exist in equilibrium-Answer
The combination of temperature and pressure at which liquids and gases cannot be distinguished from each other
8. If the work done by a force depends only on the initial and final stages and not on the path taken, then this type of force will be
Conservative Force-Answer
Non-conservative Force
Conservative as well as Non-conservative force
None of these
9. Working between which pair of following temperatures, the efficiency of a carnot engine will be maximum ?
10 Degrees F and 10 Degress R-Answer
10 Degrees F and 10 Degress C
10 Degrees R and 10 Degress C
It will be same in all the above cases
10. Dacron is a
Polyester-Answer
Polyamide
Nylon
Resin
11. Which of the following has the highest stable atom ?
Bi
Al
Cl
Pb-Answer
12. In Friedel-Crafts reaction, AlCl3 acts as a
Lewis Acid-Answer
Lewis Base
Catalyst
Reactant
13. The number of unpaired electrons in [Ni(CO)4] is
Zero-Answer
One
Three
Five
14. Iodoethane reacts with sodium to form
Pentane
Propane
Butene
Butane-Answer
15. An ideal gas has maximum density at
1 atm, 300 K
2 atm, 150 K-Answer
0.5 atm, 600 K
1 atm, 500 K
16. Which of the following metals is present in brass, bronze and german silver ?
Defence Mechanism
Hydrolysis of ATP
Trifling of Contraction-Answer
Generating right electrical potential across cell membrane
17. First ionization potential is ___________ second ionization potential.
Less than-Answer
More than
Equal to
None of these
18. n-propyl benzene is best prepared by
Friedel-Crafts Reaction
Wurtz Reaction
Wurtz-Fitting Reaction-Answer
Grignard Reaction
19. Chloroform is slowly oxidized by air to
Formly Chloride
Carbonyl Chloride-Answer
Trichloroacetic Acid
Formic Acide
20. Electrophoresis is
Movement of colloidal particle under the influence of electric field-Answer
Movement of colloidal particle under the influence of magnetic field
Movement of colloidal particle in zig-zag fashion
Scattering of light by colloidal particles
21. Rosenmund's reduction of an acyl chloride gives
Alcohol
Ester
Hydrocarbon
Aldehyde-Answer
22. Pyrophosphoric acid is
Monobasic
Dibasic-Answer
Tribasic
Basic
23. Which of the following is an example of a mathematical model ?
Area of a circle = PI x Radius^2
Volume of a cube = Length^3
Force = Mass x Acceleration
All of the above-Answer
24. The specific activity of an enzyme is relatively constant between pH 3-8. If the enzyme activity at pH 7.0 is to be modeled, which of the following would be a reasonable simplifying assumption ?
Specific activity is not dependent on temperature
Specific activity is not dependent on substrate concentration
Specific activity is not dependent on pH-Answer
All of the above
25. The bioreactor which is most commonly used in industry is the
Batch Fermenter
Fed Batch Fermenter-Answer
Continous Fermenter
Batch Continous Fermenter
26. Which of the following is correct with regards to microbial growth ?
Cells are autocatalysts and thus the rate of increase in biomass (dX/dt) keeps changing
Many factors affect cell growth
The rate of increase in biomass concentration is not constant during a fermentation
All of the above are correct-Answer
27. During a batch fermentation, when would the specific growth rate be lowest ?
During exponential phase
During the lag and stationary phase-Answer
When cells are growing at their fastest rate
Throughout the fermentation
28. Which of the following describes a limitation of the exponential growth model ?
Biomass growth is assumed to be not linked to the availability of nutrients or substrates
It does not predict when cell growth will cease
It predicts that all types of cells under all conditions will grow exponentially
All of the above are correct-Answer
29. In large scale bioreactors, dissolved oxygen levels are often so low that they restrict the rate of cell growth. In this case
Dissolved oxygen would be the growth limiting nutrient
The nitrogen source would be the growth limiting nutrient
The carbon source would be the growth limiting nutrient-Answer
Dissolved oxygen levels would not be the growth limiting nutrient
30. Which of the following is not correct ?
The Monod model is an empirical correlation
The Michaelis Menten model is a mechanistic model
The Monod model was derived from a study of the mechanism of microbial growth-Answer
The Michaelis Menten model was derived from a study of the mechanism of enzyme action
31. The technique of Nick Translation was developed by
Rigby and Paul Berg-Answer
Winkler
Roderick and Rigby
None of them
32. Which technique allows knowing the status in the interphase ?
Hybridization Microarray
Karyotyping
Fluorescence in situ Hybridization-Answer
Pedigree Analysis
33. _________ observed that protein sequences undergo variation during evolution according to certain patterns
Zuckerkandl
Pauling
Margaret Dayoff-Answer
All of them
34. Which of the following would have the highest oxygen transfer rate characteristics ?
A sparged stirred tank bioreactor being stirred at 200 rpm
A non-sparged stirred tank bioreactor being stirred at 200 rpm
A shake flask being mixed at 200 rpm
All of the above would have equivalent oxygen transfer rate characteristics
The answer is A sparged stirred tank bioreactor being stirred at 200 rpm
35. Molar heat capacity of water in equilibrium with ice at constant pressure is
Zero
Infinity
40.45 KJ K^-1 mol^-1
75.48 JK^-1 mol^-1
The answer is Zero
36. Ammonium molybdate test is used to detect the presence of
Borate
Phosphate
Chloride
Bromide
The answer is Phosphate
37. Increasing the temperature of an aqueous solution will cause
Decrease in Molality
Decrease in Molarity
Decrease in Mole Fraction
Decrease in Percentage by Weight
The answer is Decrease in Molarity
38. IUPAC name of the compound CH3CH(OH)COOH is
Lactic Acid
A-Hydroxypropanoic Acid
Carboxy Propanol
2-Hydroxypropanoic acid
The answer is 2-Hydroxypropanoic acid
39 Which of the following will not displace hydrogen ?
Ba
Pb
Ag
Sn
The answer is Ag
40. The amount of heat measure for a reaction in a bomb calorimeter is
DG
DH
DE
PDV
The answer is DE
41. Which of the following oxides is most amphoteric ?
Na2O
Al2O3
SO3
P2O5
The answer is Al2O3
42. Which among the following is most basic compound ?
Benzylamine
Aniline
Acetanilide
P-Nitroaniline
The answer is Benzylamine
43. Which of the following elements form interstitial compounds ?
Fe
Co
Ni
All of these
The answer is All of these
44 The EAN of Co in K3[Co(NH3)6] is
34
35
36
37
The answer is 36
45 The position of electron is identified by quantum numbers n and l. (i) n = 4, l = 1 (ii) n = 4, l = 0 (iii) n = 3, l = 2 (iv) n = 3, l = 1 The order of increasing energy from the lowest to highest is
(iv) < (ii) < (iii) < (i)
(ii) < (iv) < (i) < (iii)
(i) < (iii) < (ii) < (iv)
(iii) < (i) < (iv) < (ii)
The answer is (iv) < (ii) < (iii) < (i)
46. Gutta Percha is
Trans-polyisoproprene
A synthetic polymer
A very hard material
All are correct
The answer is All are correct
47. Which one of following does not give acetylene with water ?
CaC2
BaC2
SrC2
Al4C3
The answer is Al4C3
48. Normality of 0.3 M phosphoric acid (H3PO3) is
0.3
0.6
0.9
0.1
The answer is 0.6
49. ___________ technique is based on the fact that there are variations in the DNA sequence of restriction sites among different individuals and different species.
Polymer Chain Reaction
Hybridoma
Restriction Fragment Length Polymorphism
None of these
The answer is Restriction Fragment Length Polymorphism
50 Which enzyme forms phosphodiester bonds between adjacent nucleotides and covalently links two individual fragments of double stranded DNA
Alkaline Phosphates
DNA Polymerase
DNA Liqase
Exonuclease
The answer is DNA Liqase
51 Name the enzyme used to prevent unwanted self-liquation of vector DNA molecules in cleaning procedures
Alkaline Phosphates
DNA Ligase
DNA Polymerase
Helicases
The answer is Alkaline Phosphates
52. Many of the vector for use in eukaryotic cells are constructed such that they can exist in both the eukaryotic cell and E.coli. Such vectors are known as
Shuttle Passengers
Shuttle Vectors
Expression Vectors
All of these
The answer is Shuttle Vectors
53 ___________ are constructed by combining certain features of plasmid and the cos sites of the phage lambda
Hybrides
Cybrids
Cosmids
None of these
The answer is Cosmids
54 ____________ are used as vector to clone DNA fragments of more than 1 Mb in size
Yeast Artificial Chromosomes
Bacterial Artificial Chromosomes
Plant Chromosomes
All of these
The answer is Yeast Artificial Chromosomes
55 ___________ vector can accommodate upto 300-350 kb of foreign DNA
YAC
BAC
Plant
Animal
Answer BAC
56 A collection of clones representing the complete genome of an organism is called
Genomic Library
DNA Library
Inventory
None of these
Answer-Genomic Library
57. Which method is used to introduce recombinant DNA into host cell ?
Electroporation
Microinjection
Biolistics
All of the above-Answer
58. Who invented Polymerase Chain Reaction ?
Ely Lilly
Kary Mullis
Sanger
All of these
The answer is Kary Mullis
59 Who developed Dideoxynucleotide Chain termination method ?
Frederick Sanger and Andrew Coulson
Andrew Coulson and Maxam
Gilbert
All of them
The answer is Frederick Sanger and Andrew Coulson
60 Who coined the term genomics ?
Winkler
Thomas Roderick
Craig Venter
All of them
The answer is Thomas Roderick
61. ___________ primarily involves high-throughput DNA sequencing followed by assembly, organization and management of DNA sequence
Structural Genomics
Functional Genomics
Contigs
None of these
The answer is Structural Genomics
62. ____________ deals with the reconstruction of the genome to determine the biological function of genes and gene interaction
Structural Genomics
Functional Genomics
Random Libraries
Contigs
The answer is Functional Genomics
63 _________ of genomic DNA are constructed in small and edium seat plasmid vector along with genomic shotgun large unseat BAC library
Random Arrays
Mirco Arrays
Random Libraries
All of these
The answer is Random Libraries
64. BLAST means
Basic Local Alignment Search Tool
Basic Local Array Search Tool
Basic Linkage Alignment Search Technique
None of them
The answer is Basic Local Alignment Search Tool
65. ___________ is a closed culture system, which contains limited amount of nutrients
Fed-Batch Culture
Continuous Culture
Batch Culture
All of these
The answer is Batch Culture
66.If a batch culture is continuously or sequentially fed with fresh medium without remaining the growing culture, it is called
Batch Culture
Fed-Batch Culture
Continuous Culture
Another Culture
The answer is Fed-Batch Culture
67 If the temperature of saturated water is increased infinitesimally at constant entropy, the resulting state of water will be
(A) Liquid
(B) Liquid – vapor coexistence
(C) Saturated vapor
(D) Solid
68 Water is flowing under laminar conditions in a pipe of length L . If the diameter of the pipe is
doubled, for a constant volumetric flow rate, the pressure drop across the pipe
(A) decreases 2 times
(B) decreases 16 times
(C) increases 2 times
(D) increases 16 times
70 For uniform laminar flow (in the x -direction) past a flat plate at high Reynolds number, the local boundary layer thickness (? ) varies with the distance along the plate ( x ) as
